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OmniRx › Tools › Generic competition check › Tretinoin

Generic competition · all medicines · read 12 November 2026

Is there a generic of Tretinoin, and who makes it?

Tretinoin appears in 6 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 10 generic makers listed as marketed across them. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming. Where both are dated, the first generic approval came between 3 and 11.6 years after the first brand approval. This is the Orange Book's listing, not a forecast.

Compiled and checked by Vincent Wesley Couey (ORCID 0009-0005-6869-308X) from the Orange Book data files, downloaded 12 November 2026.

Not medical advice. This page reports what the FDA's Orange Book lists, not what a pharmacy has in stock, what anything costs, or whether a generic is right for you. Ask your pharmacist or prescriber about your own medicine.
Tretinoin6 dosage-form groups in the Orange Book
10generic makers listed
  1. Tretinoin appears in 6 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 10 generic makers listed as marketed across them.
  2. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming.
  3. Where both are dated, the first generic approval came between 3 and 11.6 years after the first brand approval.
  4. Patents and exclusivities are shown as listed by the application holder; the Orange Book does not rule on them, and a listed patent is not a statement that a generic is blocked. This says nothing about price, supply or quality.

Cream, Topical

Four or more generic makers listed

Brand listed as marketed: Avita, Renova and Retin-A. 5 generic makers with 14 generic products listed as marketed; the first generic approval is dated 24 December 1998.

198519901995200020052010201520202025203005brand 1988Padagis Us Llc, first approval 24 December 1998Sun Pharma Canada Inc, first approval 22 January 2019Zydus Lifesciences Ltd, first approval 25 April 2024Alembic Pharmaceuticals Ltd, first approval 29 April 2024Encube Ethicals Private Ltd, first approval 10 July 2025data date
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end
Generic maker (applicant)First approvalProducts
Padagis Us Llc24 December 19983
Sun Pharma Canada Inc22 January 20193
Zydus Lifesciences Ltd25 April 20242
Alembic Pharmaceuticals Ltd29 April 20243
Encube Ethicals Private Ltd10 July 20253

Patents and exclusivities still listed

No unexpired patent or exclusivity is listed against the marketed brand products in this group.

Gel, Topical

Four or more generic makers listed

Brand listed as marketed: Atralin, Retin-A, Retin-A Micro and Retin-A-Micro. 5 generic makers with 10 generic products listed as marketed; the first generic approval is dated 22 February 2000.

1995200020052010201520202025203005brand 1997Padagis Us Llc, first approval 22 February 2000Mylan Pharmaceuticals Inc, first approval 13 August 2015Encube Ethicals Private Ltd, first approval 22 August 2023Aurobindo Pharma Ltd, first approval 13 January 2025Amneal Pharmaceuticals Llc, first approval 14 May 2026data date
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end
Generic maker (applicant)First approvalProducts
Padagis Us Llc22 February 20002
Mylan Pharmaceuticals Inc13 August 20151
Encube Ethicals Private Ltd22 August 20234
Aurobindo Pharma Ltd13 January 20252
Amneal Pharmaceuticals Llc14 May 20261

Patents and exclusivities still listed

No unexpired patent or exclusivity is listed against the marketed brand products in this group.

Capsule, Oral

One to three generic makers listed

Every brand product here is listed as discontinued. 2 generic makers with 2 generic products listed as marketed; the first generic approval is dated 22 June 2007.

1995200020052010201520202025203002brand 1995Ph Health Ltd, first approval 24 October 2012Glenmark Pharmaceuticals Ltd, first approval 23 December 2016data date
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end
Generic maker (applicant)First approvalProducts
Ph Health Ltd24 October 20121
Glenmark Pharmaceuticals Ltd23 December 20161

Patents and exclusivities still listed

No unexpired patent or exclusivity is listed against the marketed brand products in this group.

Solution, Topical

Nothing listed as marketed

Every brand product here is listed as discontinued. No generic is listed as marketed (2 generic products listed as discontinued).

Patents and exclusivities still listed

No unexpired patent or exclusivity is listed against the marketed brand products in this group.

Lotion, Topical

Brand listed, no generic listed as marketed

Brand listed as marketed: Altreno. No generic is listed as marketed.

20152020202520302035204001brand 2018data datePatent 10653656 listed to expire 22 August 2038Patent 11324710 listed to expire 22 August 2038
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end

Patents and exclusivities still listed

  • 22 August 2038Patent 10653656 drug product
  • 22 August 2038Patent 11324710

Swab, Topical

Nothing listed as marketed

Every brand product here is listed as discontinued. No generic is listed as marketed.

Patents and exclusivities still listed

No unexpired patent or exclusivity is listed against the marketed brand products in this group.

US Food and Drug Administration, Orange Book data files, downloaded 12 November 2026. A listed patent is not a ruling that a generic is blocked, and no figure here says anything about price, supply or quality. Check the Orange Book.

Where can you go from this result?

Open it in the check to search another medicine, or see every brand with no generic listed. The FDA explains generic approval in how generic drugs are approved and the FDA generic drug facts, and the Orange Book itself is the FDA Orange Book. To check what is available now, ask your pharmacist, and see the FDA drug shortages page.