interaction records 54 assistance programs 55 0 personal data stored
OmniRx › Tools › Generic competition check › Pemetrexed Disodium

Generic competition · all medicines · read 12 November 2026

Is there a generic of Pemetrexed Disodium, and who makes it?

Pemetrexed Disodium appears in 2 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 13 generic makers listed as marketed across them. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming. Where both are dated, the first generic approval came 18.3 years after the first brand approval. This is the Orange Book's listing, not a forecast.

Compiled and checked by Vincent Wesley Couey (ORCID 0009-0005-6869-308X) from the Orange Book data files, downloaded 12 November 2026.

Not medical advice. This page reports what the FDA's Orange Book lists, not what a pharmacy has in stock, what anything costs, or whether a generic is right for you. Ask your pharmacist or prescriber about your own medicine.
Pemetrexed Disodium2 dosage-form groups in the Orange Book
13generic makers listed
  1. Pemetrexed Disodium appears in 2 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 13 generic makers listed as marketed across them.
  2. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming.
  3. Where both are dated, the first generic approval came 18.3 years after the first brand approval.
  4. Patents and exclusivities are shown as listed by the application holder; the Orange Book does not rule on them, and a listed patent is not a statement that a generic is blocked. This says nothing about price, supply or quality.

Powder, Intravenous

Four or more generic makers listed

Brand listed as marketed: Alimta. 13 generic makers with 34 generic products listed as marketed; the first generic approval is dated 25 May 2022.

2000200520102015202020252030013brand 2004Accord Healthcare Inc, first approval 25 May 2022Apotex Inc, first approval 25 May 2022Dr Reddys Laboratories Ltd, first approval 25 May 2022Eugia Pharma Specialities Ltd, first approval 25 May 2022Fresenius Kabi Usa Llc, first approval 25 May 2022Jiangsu Hansoh Pharmaceutical Group Co Ltd, first approval 25 May 2022Nang Kuang Pharmaceutical Co Ltd, first approval 25 May 2022Qilu Pharmaceutical Hainan Co Ltd, first approval 25 May 2022Somerset Therapeutics Llc, first approval 25 May 2022Zydus Pharmaceuticals Usa Inc, first approval 25 May 2022Meitheal Pharmaceuticals Inc, first approval 13 December 2022Prinston Pharmaceutical Inc, first approval 11 December 2023Hetero Labs Ltd Unit Vi, first approval 14 June 2024data date
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end
Generic maker (applicant)First approvalProducts
Accord Healthcare Inc25 May 20223
Apotex Inc25 May 20223
Dr Reddys Laboratories Ltd25 May 20223
Eugia Pharma Specialities Ltd25 May 20223
Fresenius Kabi Usa Llc25 May 20224
Jiangsu Hansoh Pharmaceutical Group Co Ltd25 May 20222
Nang Kuang Pharmaceutical Co Ltd25 May 20222
Qilu Pharmaceutical Hainan Co Ltd25 May 20222
Somerset Therapeutics Llc25 May 20222
Zydus Pharmaceuticals Usa Inc25 May 20223
Meitheal Pharmaceuticals Inc13 December 20224
Prinston Pharmaceutical Inc11 December 20231

1 more makers are listed in the data.

Patents and exclusivities still listed

No unexpired patent or exclusivity is listed against the marketed brand products in this group.

Solution, Intravenous

Brand listed, no generic listed as marketed

Brand listed as marketed: Pemetrexed and Pemetrexed Disodium. No generic is listed as marketed.

202020252030203501brand 2022data datePatent 11147817 listed to expire 26 March 2035
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end

Patents and exclusivities still listed

  • 26 March 2035Patent 11147817 drug product

US Food and Drug Administration, Orange Book data files, downloaded 12 November 2026. A listed patent is not a ruling that a generic is blocked, and no figure here says anything about price, supply or quality. Check the Orange Book.

Where can you go from this result?

Open it in the check to search another medicine, or see every brand with no generic listed. The FDA explains generic approval in how generic drugs are approved and the FDA generic drug facts, and the Orange Book itself is the FDA Orange Book. To check what is available now, ask your pharmacist, and see the FDA drug shortages page.