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OmniRx › Tools › Generic competition check › Lotilaner

Generic competition · all medicines · read 12 November 2026

Is there a generic of Lotilaner, and who makes it?

Lotilaner appears in 1 dosage-form group in the FDA Orange Book as of 12 November 2026, with no generic maker listed as marketed. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming. This is the Orange Book's listing, not a forecast.

Compiled and checked by Vincent Wesley Couey (ORCID 0009-0005-6869-308X) from the Orange Book data files, downloaded 12 November 2026.

Not medical advice. This page reports what the FDA's Orange Book lists, not what a pharmacy has in stock, what anything costs, or whether a generic is right for you. Ask your pharmacist or prescriber about your own medicine.
Lotilaner1 dosage-form group in the Orange Book
0generic makers listed
  1. Lotilaner appears in 1 dosage-form group in the FDA Orange Book as of 12 November 2026, with no generic maker listed as marketed.
  2. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming.
  3. Patents and exclusivities are shown as listed by the application holder; the Orange Book does not rule on them, and a listed patent is not a statement that a generic is blocked. This says nothing about price, supply or quality.

Solution/Drops, Ophthalmic

Brand listed, no generic listed as marketed

Brand listed as marketed: Xdemvy. No generic is listed as marketed.

2020202520302035204001brand 2023data datePatent 8383659 listed to expire 17 January 2030Patent 11690827 listed to expire 14 December 2038Patent 11690826 listed to expire 14 December 2038Patent 11197847 listed to expire 14 December 2038Patent 10835517 listed to expire 14 December 2038Patent 12171750 listed to expire 14 December 2038Patent 11752137 listed to expire 14 December 2038Patent 12213964 listed to expire 14 December 2038Patent 12364685 listed to expire 14 December 2038Exclusivity NCE to 24 July 2028
generic makers listed as marketed, by first approvallisted patent expiryexclusivity end

Patents and exclusivities still listed

  • 24 July 2028Exclusivity NCE Xdemvy
  • 17 January 2030Patent 8383659 drug substance
  • 14 December 2038Patent 11690827
  • 14 December 2038Patent 11690826
  • 14 December 2038Patent 11197847
  • 14 December 2038Patent 10835517
  • 14 December 2038Patent 12171750
  • 14 December 2038Patent 11752137 drug product
  • 14 December 2038Patent 12213964 drug product

1 more patents are listed.

US Food and Drug Administration, Orange Book data files, downloaded 12 November 2026. A listed patent is not a ruling that a generic is blocked, and no figure here says anything about price, supply or quality. Check the Orange Book.

Where can you go from this result?

Open it in the check to search another medicine, or see every brand with no generic listed. The FDA explains generic approval in how generic drugs are approved and the FDA generic drug facts, and the Orange Book itself is the FDA Orange Book. To check what is available now, ask your pharmacist, and see the FDA drug shortages page.