Generic competition · all medicines · read 12 November 2026
Is there a generic of Hydrochlorothiazide, and who makes it?
Hydrochlorothiazide appears in 4 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 12 generic makers listed as marketed across them. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming. Where both are dated, the first generic approval came 3.1 years after the first brand approval. This is the Orange Book's listing, not a forecast.
Compiled and checked by Vincent Wesley Couey (ORCID 0009-0005-6869-308X) from the Orange Book data files, downloaded 12 November 2026.
- Hydrochlorothiazide appears in 4 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 12 generic makers listed as marketed across them.
- 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming.
- Where both are dated, the first generic approval came 3.1 years after the first brand approval.
- Patents and exclusivities are shown as listed by the application holder; the Orange Book does not rule on them, and a listed patent is not a statement that a generic is blocked. This says nothing about price, supply or quality.
Tablet, Oral
Four or more generic makers listed
Every brand product here is listed as discontinued. 9 generic makers with 22 generic products listed as marketed; the first generic approval is dated 3 February 1982.
| Generic maker (applicant) | First approval | Products |
|---|---|---|
| Oxford Pharmaceuticals Llc | not dated | 2 |
| Actavis Elizabeth Llc | 27 February 2007 | 1 |
| Leading Pharma Llc | 16 March 2007 | 3 |
| Aurobindo Pharma Ltd | 20 July 2007 | 2 |
| Unichem Laboratories Ltd | 15 August 2008 | 3 |
| Accord Healthcare Inc | 24 September 2012 | 3 |
| Sciegen Pharmaceuticals Inc | 23 July 2014 | 2 |
| Heritage Pharmaceuticals Inc Dba Avet Pharmaceuticals Inc | 2 May 2023 | 3 |
| Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa | 19 September 2024 | 3 |
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
Capsule, Oral
Four or more generic makers listed
Brand listed as marketed: Microzide. 5 generic makers with 5 generic products listed as marketed; the first generic approval is dated 28 January 2000.
| Generic maker (applicant) | First approval | Products |
|---|---|---|
| Prinston Pharmaceutical Inc | 17 September 2002 | 1 |
| Aurobindo Pharma Ltd | 18 September 2007 | 1 |
| Jubilant Cadista Pharmaceuticals Inc | 11 February 2008 | 1 |
| Unichem Laboratories Ltd | 19 January 2010 | 1 |
| Sciegen Pharmaceuticals Inc | 14 January 2019 | 1 |
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
Solution, Oral
Generics listed, no brand listed
No brand application is listed. 1 generic maker with 1 generic product listed as marketed; the first generic approval is dated 2 July 1984.
| Generic maker (applicant) | First approval | Products |
|---|---|---|
| Rubicon Research Ltd | 7 October 2026 | 1 |
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
For Suspension, Oral
Brand listed, no generic listed as marketed
Brand listed as marketed: Inzirqo. No generic is listed as marketed.
Patents and exclusivities still listed
- 23 January 2044Patent 11878022 drug product
US Food and Drug Administration, Orange Book data files, downloaded 12 November 2026. A listed patent is not a ruling that a generic is blocked, and no figure here says anything about price, supply or quality. Check the Orange Book.
Where can you go from this result?
Open it in the check to search another medicine, or see every brand with no generic listed. The FDA explains generic approval in how generic drugs are approved and the FDA generic drug facts, and the Orange Book itself is the FDA Orange Book. To check what is available now, ask your pharmacist, and see the FDA drug shortages page.