Generic competition · all medicines · read 12 November 2026
Is there a generic of Amantadine Hydrochloride, and who makes it?
Amantadine Hydrochloride appears in 5 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 16 generic makers listed as marketed across them. 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming. Where both are dated, the first generic approval came 7 years after the first brand approval. This is the Orange Book's listing, not a forecast.
Compiled and checked by Vincent Wesley Couey (ORCID 0009-0005-6869-308X) from the Orange Book data files, downloaded 12 November 2026.
- Amantadine Hydrochloride appears in 5 dosage-form groups in the FDA Orange Book as of 12 November 2026, with 16 generic makers listed as marketed across them.
- 1 group has a brand listed as marketed and no generic listed as marketed. The data does not state why, and it does not state that one is coming.
- Where both are dated, the first generic approval came 7 years after the first brand approval.
- Patents and exclusivities are shown as listed by the application holder; the Orange Book does not rule on them, and a listed patent is not a statement that a generic is blocked. This says nothing about price, supply or quality.
Capsule, Oral
Four or more generic makers listed
Every brand product here is listed as discontinued. 11 generic makers with 11 generic products listed as marketed; the first generic approval is dated 5 August 1986.
| Generic maker (applicant) | First approval | Products |
|---|---|---|
| Upsher Smith Laboratories Llc | 5 August 1986 | 1 |
| Sandoz Inc | 18 February 1987 | 1 |
| Bionpharma Inc | 29 May 2008 | 1 |
| Zydus Pharmaceuticals Usa Inc | 31 May 2016 | 1 |
| Strides Pharma Global Pte Ltd | 7 June 2017 | 1 |
| Heritage Pharma Labs Inc | 12 June 2017 | 1 |
| Alembic Pharmaceuticals Ltd | 21 June 2017 | 1 |
| Rising Pharma Holdings Inc | 2 March 2020 | 1 |
| Rubicon Research Ltd | 21 May 2020 | 1 |
| Onesource Softgels Pte Ltd | 18 February 2022 | 1 |
| Humanwell Puracap Pharmaceutical Wuhan Co Ltd | 20 December 2022 | 1 |
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
Syrup, Oral
Four or more generic makers listed
Every brand product here is listed as discontinued. 4 generic makers with 5 generic products listed as marketed; the first generic approval is dated 30 October 1990.
| Generic maker (applicant) | First approval | Products |
|---|---|---|
| Chartwell Rx Sciences Llc | 28 June 1993 | 1 |
| Aurobindo Pharma Usa Inc | 28 October 1994 | 1 |
| Pharmaceutical Associates Inc | 17 July 1995 | 1 |
| Pharmobedient Consulting Llc | 24 December 1998 | 2 |
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
Tablet, Oral
Four or more generic makers listed
Every brand product here is listed as discontinued. 5 generic makers with 5 generic products listed as marketed; the first generic approval is dated 16 December 2002.
| Generic maker (applicant) | First approval | Products |
|---|---|---|
| Upsher Smith Laboratories Llc | 16 December 2002 | 1 |
| Strides Pharma Global Pte Ltd | 9 June 2017 | 1 |
| Pharmobedient Consulting Llc | 10 March 2020 | 1 |
| Alembic Pharmaceuticals Ltd | 15 October 2020 | 1 |
| Zhejiang Jutai Pharmaceutical Co Ltd | 26 September 2024 | 1 |
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
Tablet, Extended Release, Oral
Nothing listed as marketed
Every brand product here is listed as discontinued. No generic is listed as marketed.
Patents and exclusivities still listed
No unexpired patent or exclusivity is listed against the marketed brand products in this group.
Capsule, Extended Release, Oral
Brand listed, no generic listed as marketed
Brand listed as marketed: Gocovri. No generic is listed as marketed (1 generic product listed as discontinued).
Patents and exclusivities still listed
- 22 January 2028Patent 8389578
- 2 December 2030Patent 9867792
- 2 December 2030Patent 9867791
- 2 December 2030Patent 9877933
- 2 December 2030Patent 8741343
- 2 December 2030Patent 9867793
- 2 December 2030Patent 11197835
- 17 June 2034Patent 10646456
5 more patents are listed.
US Food and Drug Administration, Orange Book data files, downloaded 12 November 2026. A listed patent is not a ruling that a generic is blocked, and no figure here says anything about price, supply or quality. Check the Orange Book.
Where can you go from this result?
Open it in the check to search another medicine, or see every brand with no generic listed. The FDA explains generic approval in how generic drugs are approved and the FDA generic drug facts, and the Orange Book itself is the FDA Orange Book. To check what is available now, ask your pharmacist, and see the FDA drug shortages page.