Drug data · Medicare negotiated prices · pharmacy acquisition cost
Medicare's negotiated prices next to what pharmacies pay, drug by drug
For 76 drug packages, two federal files publish a price per unit: the Medicare negotiated price (CMS, file of November 2, 2026) and NADAC, the survey-based benchmark of what retail pharmacies pay to buy the drug (CMS, week of November 4, 2026). This page puts them side by side. Across brand-name packages the median negotiated price is 37% of the pharmacy benchmark.
37%median negotiated price as a share of NADAC, brand-name packages (71), not weighted by volume
6brand-name packages where the negotiated price is above the benchmark
5generic-class packages listed in the CMS file, kept apart below
How far below the pharmacy benchmark each negotiated price sits
Each row is one drug. The line at 100% is the NADAC price per unit. The dot is the median negotiated price per unit as a share of it; the whisker spans the packages of that drug (strengths and package sizes differ). Brand-name packages only.
Swipe to read across
Every package, side by side
Price per unit (a tablet, a millilitre or a gram, as the files state). The last column is the negotiated price as a share of NADAC.
| Drug | NDC | Product | Unit | Negotiated | NADAC | Share | Class |
|---|---|---|---|---|---|---|---|
| Eliquis | 00003-0893-21 | ELIQUIS 2.5 MG TABLET | EA | $4.15 | $5.51 | 75% | brand |
| Eliquis | 00003-0893-31 | ELIQUIS 2.5 MG TABLET | EA | $4.15 | $5.51 | 75% | brand |
| Eliquis | 00003-0894-21 | ELIQUIS 5 MG TABLET | EA | $4.15 | $5.52 | 75% | brand |
| Eliquis | 00003-0894-31 | ELIQUIS 5 MG TABLET | EA | $4.15 | $5.52 | 75% | brand |
| Eliquis | 00003-0894-70 | ELIQUIS 5 MG TABLET | EA | $4.15 | $5.52 | 75% | brand |
| Eliquis | 00003-3764-74 | ELIQUIS DVT-PE TREATMENT 30-DAY STARTER 5 MG PACK | EA | $4.15 | $5.51 | 75% | brand |
| Enbrel | 58406-0010-04 | ENBREL 25 MG/0.5 ML SYRINGE | ML | $584 | $2,084 | 28% | brand |
| Enbrel | 58406-0021-04 | ENBREL 50 MG/ML SYRINGE | ML | $584 | $2,081 | 28% | brand |
| Enbrel | 58406-0032-04 | ENBREL 50 MG/ML SURECLICK | ML | $584 | $2,084 | 28% | brand |
| Enbrel | 58406-0044-04 | ENBREL 50 MG/ML MINI CARTRIDGE | ML | $584 | $2,082 | 28% | brand |
| Enbrel | 58406-0044-24 | ENBREL 50 MG/ML MINI CARTRIDGE | ML | $584 | $2,082 | 28% | brand |
| Entresto | 00078-0659-20 | ENTRESTO 24 MG-26 MG TABLET | EA | $5.23 | $11.59 | 45% | brand |
| Entresto | 00078-0659-67 | ENTRESTO 24 MG-26 MG TABLET | EA | $5.23 | $11.59 | 45% | brand |
| Entresto | 00078-0696-20 | ENTRESTO 97 MG-103 MG TABLET | EA | $5.23 | $11.59 | 45% | brand |
| Entresto | 00078-0696-67 | ENTRESTO 97 MG-103 MG TABLET | EA | $5.23 | $11.59 | 45% | brand |
| Entresto | 00078-0777-20 | ENTRESTO 49 MG-51 MG TABLET | EA | $5.23 | $11.56 | 45% | brand |
| Entresto | 00078-0777-67 | ENTRESTO 49 MG-51 MG TABLET | EA | $5.23 | $11.56 | 45% | brand |
| Entresto | 00078-1231-20 | ENTRESTO SPRINKLE 6-6 MG PELLET | EA | $5.52 | $11.62 | 47% | brand |
| Entresto | 00078-1238-20 | ENTRESTO SPRINKLE 15-16 MG PLT | EA | $5.65 | $11.61 | 49% | brand |
| Farxiga | 00310-6205-30 | FARXIGA 5 MG TABLET | EA | $6.05 | $12.07 | 50% | brand |
| Farxiga | 00310-6205-90 | FARXIGA 5 MG TABLET | EA | $6.05 | $12.07 | 50% | brand |
| Farxiga | 00310-6210-30 | FARXIGA 10 MG TABLET | EA | $6.05 | $12.08 | 50% | brand |
| Farxiga | 00310-6210-39 | FARXIGA 10 MG TABLET | EA | $6.05 | $12.08 | 50% | brand |
| Farxiga | 00310-6210-90 | FARXIGA 10 MG TABLET | EA | $6.05 | $12.08 | 50% | brand |
| Farxiga | 66993-0456-30 | DAPAGLIFLOZIN 5 MG TABLET | EA | $6.05 | $0.163 | 3710% | generic |
| Farxiga | 66993-0457-30 | DAPAGLIFLOZIN 10 MG TABLET | EA | $6.05 | $0.184 | 3282% | generic |
| Januvia | 00006-0112-01 | JANUVIA 50 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0112-28 | JANUVIA 50 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0112-31 | JANUVIA 50 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0112-54 | JANUVIA 50 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0221-01 | JANUVIA 25 MG TABLET | EA | $3.91 | $10.54 | 37% | brand |
| Januvia | 00006-0221-28 | JANUVIA 25 MG TABLET | EA | $3.91 | $10.54 | 37% | brand |
| Januvia | 00006-0221-31 | JANUVIA 25 MG TABLET | EA | $3.91 | $10.54 | 37% | brand |
| Januvia | 00006-0221-54 | JANUVIA 25 MG TABLET | EA | $3.91 | $10.54 | 37% | brand |
| Januvia | 00006-0277-01 | JANUVIA 100 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0277-28 | JANUVIA 100 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0277-31 | JANUVIA 100 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0277-54 | JANUVIA 100 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Januvia | 00006-0277-82 | JANUVIA 100 MG TABLET | EA | $3.91 | $10.55 | 37% | brand |
| Jardiance | 00597-0152-30 | JARDIANCE 10 MG TABLET | EA | $6.79 | $11.19 | 61% | brand |
| Jardiance | 00597-0152-37 | JARDIANCE 10 MG TABLET | EA | $6.79 | $11.19 | 61% | brand |
| Jardiance | 00597-0152-90 | JARDIANCE 10 MG TABLET | EA | $6.79 | $11.19 | 61% | brand |
| Jardiance | 00597-0153-30 | JARDIANCE 25 MG TABLET | EA | $6.79 | $11.19 | 61% | brand |
| Jardiance | 00597-0153-37 | JARDIANCE 25 MG TABLET | EA | $6.79 | $11.19 | 61% | brand |
| Jardiance | 00597-0153-90 | JARDIANCE 25 MG TABLET | EA | $6.79 | $11.19 | 61% | brand |
| Novolog | 00169-3201-11 | FIASP 100 UNIT/ML VIAL | ML | $6.96 | $6.92 | 101% | brand |
| Novolog | 00169-3204-15 | FIASP 100 UNIT/ML FLEXTOUCH | ML | $8.96 | $8.91 | 101% | brand |
| Novolog | 00169-3205-15 | FIASP PENFILL 100 UNIT/ML CART | ML | $8.61 | $8.54 | 101% | brand |
| Novolog | 00169-3206-15 | FIASP PUMPCART 100 UNIT/ML | ML | $6.96 | $8.57 | 81% | brand |
| Novolog | 00169-3303-12 | NOVOLOG PENFILL 100 UNIT/ML | ML | $8.61 | $8.57 | 100% | brand |
| Novolog | 00169-6339-10 | NOVOLOG 100 UNIT/ML FLEXPEN | ML | $8.96 | $8.93 | 100% | brand |
| Novolog | 00169-7501-11 | NOVOLOG 100 UNIT/ML VIAL | ML | $6.96 | $6.93 | 100% | brand |
| Novolog | 73070-0100-11 | INSULIN ASPART 100 UNIT/ML VL | ML | $3.48 | $6.95 | 50% | generic |
| Novolog | 73070-0102-15 | INSULIN ASPART PENFILL 100 UNIT/ML CARTRIDGE | ML | $4.31 | $8.57 | 50% | generic |
| Novolog | 73070-0103-15 | INSULIN ASPART FLEXPEN 100 UNIT/ML PEN | ML | $4.48 | $8.96 | 50% | generic |
| Stelara | 57894-0060-03 | STELARA 45 MG/0.5 ML SYRINGE | ML | $8,980 | $29,874 | 30% | brand |
| Stelara | 57894-0061-03 | STELARA 90 MG/ML SYRINGE | ML | $8,980 | $29,793 | 30% | brand |
| Xarelto | 50458-0575-01 | XARELTO 1 MG/ML SUSPENSION | ML | $1.33 | $3.76 | 35% | brand |
| Xarelto | 50458-0577-01 | XARELTO 2.5 MG TABLET | EA | $3.44 | $9.78 | 35% | brand |
| Xarelto | 50458-0577-10 | XARELTO 2.5 MG TABLET | EA | $3.44 | $9.78 | 35% | brand |
| Xarelto | 50458-0577-18 | XARELTO 2.5 MG TABLET | EA | $3.44 | $9.78 | 35% | brand |
| Xarelto | 50458-0577-60 | XARELTO 2.5 MG TABLET | EA | $3.44 | $9.78 | 35% | brand |
| Xarelto | 50458-0578-01 | XARELTO 15 MG TABLET | EA | $6.88 | $19.53 | 35% | brand |
| Xarelto | 50458-0578-10 | XARELTO 15 MG TABLET | EA | $6.88 | $19.53 | 35% | brand |
| Xarelto | 50458-0578-30 | XARELTO 15 MG TABLET | EA | $6.88 | $19.53 | 35% | brand |
| Xarelto | 50458-0578-90 | XARELTO 15 MG TABLET | EA | $6.88 | $19.53 | 35% | brand |
| Xarelto | 50458-0579-01 | XARELTO 20 MG TABLET | EA | $6.88 | $19.54 | 35% | brand |
| Xarelto | 50458-0579-10 | XARELTO 20 MG TABLET | EA | $6.88 | $19.54 | 35% | brand |
| Xarelto | 50458-0579-30 | XARELTO 20 MG TABLET | EA | $6.88 | $19.54 | 35% | brand |
| Xarelto | 50458-0579-89 | XARELTO 20 MG TABLET | EA | $6.88 | $19.54 | 35% | brand |
| Xarelto | 50458-0579-90 | XARELTO 20 MG TABLET | EA | $6.88 | $19.54 | 35% | brand |
| Xarelto | 50458-0580-01 | XARELTO 10 MG TABLET | EA | $6.87 | $19.52 | 35% | brand |
| Xarelto | 50458-0580-10 | XARELTO 10 MG TABLET | EA | $6.87 | $19.52 | 35% | brand |
| Xarelto | 50458-0580-30 | XARELTO 10 MG TABLET | EA | $6.87 | $19.52 | 35% | brand |
| Xarelto | 50458-0580-90 | XARELTO 10 MG TABLET | EA | $6.87 | $19.52 | 35% | brand |
| Xarelto | 50458-0584-51 | XARELTO DVT-PE TREATMENT 30-DAY STARTER 15-20 MG PACK | EA | $6.85 | $19.47 | 35% | brand |
Generic-class packages. 5 packages in the CMS file are classed as generic by NADAC. Where a generic is on the market it can cost far less than the negotiated price of the brand-name drug, so a share above 100% there reflects generic competition, not an error. They are excluded from the median above.
What the CMS file already schedules for later
The CMS file is updated at least once a year and whenever a package is added or removed. It already carries 399 rows dated after today: 85 inflation, 59 deselect, 229 new ipay, 14 new ndc, 12 hcpcs code removed. The inflation adjustments below show the 30-day-equivalent price now and the price that takes effect on the date shown.
| Drug | NDC | Now, 30 days | Scheduled | Takes effect |
|---|---|---|---|---|
| Eliquis | 00003-0893-21 | $231 | $237 | January 1, 2027 |
| Enbrel | 58406-0010-01 | $2,355 | $2,419 | January 1, 2027 |
| Farxiga | 00003-1427-11 | $179 | $183 | January 1, 2027 |
| Imbruvica | 57962-0007-12 | $9,319 | $9,571 | January 1, 2027 |
| Januvia | 00006-0112-01 | $113 | $116 | January 1, 2027 |
| Jardiance | 00597-0152-30 | $197 | $202 | January 1, 2027 |
How to read this, and what it does not say
- What the negotiated price is. The price CMS agreed with the manufacturer for a selected drug under Medicare's negotiation program, applying to Medicare Part D. It is not the price a person with other coverage, or no coverage, pays.
- What NADAC is. A weekly national average of what retail community pharmacies pay to acquire a drug, from a survey of invoices. It excludes rebates and discounts and is not what any one pharmacy paid.
- What this page does not claim. It does not say what any pharmacy earns or loses, what a patient pays, or what Medicare saves. The comparison is by package, not weighted by how many prescriptions are filled, so the median is a description of the packages, not of spending.
- How the join works. The CMS file gives the negotiated price per unit at the 9-digit NDC level; NADAC gives a price per unit for each 11-digit NDC. We compare a package's NADAC price with the negotiated per-unit price for its 9-digit product, and only where the unit matches.
Sources and terms. CMS Medicare Drug Price Negotiation Program, Selected Drug List and Maximum Fair Price data file, November 2, 2026 (the CMS page states no licence or restriction); CMS NADAC from data.medicaid.gov under the dataset labels recorded in the OmniRx licence ledger. The comparison is an OmniRx calculation, stored with its sources in the OmniRx data library. Free to cite with attribution; bulk and white-label use are licensed. Report an error through the contact page.