{
 "page": "https://omnirx.org/conditions/metastatic-melanoma/trametinib-dimethyl-sulfoxide",
 "edition": "2026-11",
 "editionRoot": "006ab9a329709cbe",
 "license": "https://omnirx.org/license",
 "generated": "2026-11-11",
 "condition": {
  "id": "metastatic-melanoma",
  "name": "Metastatic Melanoma"
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 "drug": {
  "ingredient": "Trametinib Dimethyl Sulfoxide",
  "brands": [
   "Mekinist"
  ]
 },
 "orderIsRanking": false,
 "orderNote": "Fixed order: the FDA label, public Medicare facts, the manufacturer, charities, research access. It is not a ranking and no saving is computed.",
 "routes": [
  {
   "id": "label",
   "title": "Why this drug and this condition are paired",
   "found": true,
   "quote": "MEKINIST is a kinase inhibitor indicated as a single agent for the treatment of BRAF-inhibitor treatment-naïve patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.",
   "context": "indication",
   "source": "https://api.fda.gov/drug/label.json?search=set_id:%220002ad27-779d-42ab-83b5-bc65453412a1%22&limit=1",
   "readOn": "2026-11-10",
   "fact_id": "233643f8bee315c729ba430a"
  },
  {
   "id": "part-d",
   "title": "Medicare Part D: the yearly out-of-pocket threshold",
   "found": true,
   "text": "$2,400 in 2027 ($2,100 in 2026)",
   "source": "https://www.cms.gov/files/document/2027-announcement.pdf",
   "readOn": "2026-11-08"
  },
  {
   "id": "price",
   "title": "Medicare negotiated price",
   "found": false,
   "usd30DaySupply": null,
   "effective": null,
   "source": null,
   "readOn": null
  },
  {
   "id": "program",
   "title": "Manufacturer and foundation programs",
   "found": true,
   "programs": [
    {
     "name": "Novartis Patient Assistance Foundation (NPAF)",
     "url": "https://pap.novartis.com/medications-list/",
     "programPageIsExternal": true,
     "inCurrentList": true,
     "note": null,
     "listKind": "NPAF medications list",
     "status": null,
     "statusRead": null,
     "fact_id": "99ce5f307e9b1fdfaf2364a3"
    }
   ]
  },
  {
   "id": "funds",
   "title": "Charitable funds for Metastatic Melanoma",
   "found": true,
   "fundsHeld": 2,
   "open": 0,
   "readOn": "2026-11-08",
   "openFunds": [],
   "hubUrl": "https://omnirx.org/conditions/metastatic-melanoma"
  },
  {
   "id": "trials",
   "title": "Clinical trial access",
   "found": false,
   "recruitingInterventionalTrials": null,
   "source": null,
   "readOn": null,
   "fact_id": null
  }
 ]
}